Published: 14 September 2024 | MedicalNewsToday
Nephrogenic diabetes insipidus is a rare condition that results in excessive urination and thirst. It occurs when the kidneys no longer respond to the hormone arginine vasopressin (AVP).
Symptoms occur when the kidneys do not respond or are resistant to AVP — a hormone that triggers the kidneys to conserve water. Consequently, researchers have renamed nephrogenic diabetes insipidus to arginine vasopressin disorder resistance (AVP-R).
When someone has AVP-R, the main symptoms include a frequent need to pass light-colored urine and excessive thirst. People are more likely to develop AVP-R when they have a family history of the disease or are taking medication that can increase the amount of urine they produce.
Generally, treatment involves the prevention of severe dehydration.